Hailey Bieber Says She's "Never Gonna Age" Thanks to NAD+ IV Drips, Here's What Doctors Actually Say
NAD+ IV therapy is the priciest common item on nearly every biohacking clinic menu, and a peer-reviewed 2026 systematic review just complicated the marketing pitch.
What’s Actually in an NAD+ IV Bag?
NAD+ IV bags contain nicotinamide adenine dinucleotide mixed with saline solution, dripped into a vein over one to four hours per session.
NAD+ is a coenzyme found in every cell that helps convert food into cellular energy and supports DNA repair. Clinics market the IV route because NAD+ is poorly absorbed as a standalone oral supplement, making intravenous delivery the most direct way to get the molecule itself into circulation.
The infusion is what celebrities reference when they discuss “NAD drips” at wellness studios. At Restore Hyper Wellness, a promotional entry-level NAD+ bundle starts at $79. At Next Health, a single full session can run $500 to $1,000. Session length depends on the dose and the clinic’s protocol, which is why drips can take anywhere from a single hour to most of an afternoon.
Do Doctors Say NAD+ IV Therapy Works for Anti-Aging?
A peer-reviewed systematic review published in April 2026 found that no human trial meeting scientific inclusion criteria tested IV or intramuscular NAD+ itself for anti-aging or wellness outcomes.
The PRISMA-guided review by Cory Gallagher and Owoturo Oluwaseun Emmanuel ran in Ageing Research Reviews and is available on PubMed. The authors screened studies from 2010 through 2025 and identified 113 eligible studies, 33 of them in humans. Only one nonrandomized IV study qualified, and it tested NMN, a precursor to NAD+, rather than NAD+ itself.
That study contributed safety data only. Oral NAD+ precursors NR and NMN had a stronger human evidence base in the same review, though functional outcomes were still mixed. The lead author disclosed a conflict of interest involving an ownership stake in a management company that serves an aesthetics clinic, though that clinic doesn’t offer NAD+ infusions. A lack of qualifying trials isn’t the same as evidence of harm.
How Much Does an NAD+ IV Therapy Session Cost?
A single NAD+ IV session ranges from a $79 promotional entry-level bundle at Restore Hyper Wellness to $500 to $1,000 per session at Next Health.
NAD+ is the priciest common line item on most biohacking clinic menus, which is part of why it draws attention. Cheaper options at the same studios include standard IV drips at $99 to $199 and cryotherapy at $50. Pricing varies by studio, dose and provider, so these figures should be treated as examples rather than universal rates. Some clinics bundle NAD+ with other vitamins or amino acids, which can push the total higher.
The promotional entry price at Restore is designed to bring new clients in the door, while the full Next Health range reflects a higher-dose protocol marketed to longevity-focused customers. Ask for an itemized rate sheet before booking.
Is NAD+ IV Therapy Safe According to Doctors?
Dr. Amanda Kahn, a board-certified internist and longevity medicine specialist, told TODAY she doesn’t recommend IV NAD+ because of dosing concerns and infection risk at less regulated med spas.
“I am not a proponent of IV therapy because I think you can get too much at once,” Kahn said. She also flagged added infection risk depending on who’s administering the drip, particularly at less regulated med spas. The 2026 systematic review found a lack of qualifying human trials testing IV NAD+ for anti-aging, but that absence isn’t the same as evidence of harm.
Separately, NMN, an oral NAD+ precursor, had been excluded from the dietary supplement category since 2022 over an earlier drug investigation, but the FDA reversed that position in September 2025, confirming NMN can be sold as a supplement again. Patients considering NAD+ IV therapy should ask who’s inserting the line, what dose is being used and whether the clinic has medical oversight on site.
Why Do Celebrities Like Hailey Bieber Love NAD+ IV Therapy?
On a 2022 episode of The Kardashians, Hailey Bieber said she was “going to NAD for the rest of my life”, helping turn the drip into a wellness status symbol.
Bieber’s endorsement and other celebrity mentions provide cultural context for the surge in interest, not evidence the treatment works for anti-aging. That same reporting has linked the trend to Hailey and Justin Bieber and the broader Hollywood biohacking scene.
The 2026 systematic review didn’t identify qualifying human trials supporting the anti-aging pitch that celebrity marketing leans on. Readers weighing the trend should separate cultural buzz from clinical evidence and ask whether the promised benefit has been tested in people at all.
This article was created by content specialists using various tools, including AI.
