With a victory on Sunday against the Houston Texans, Chiefs quarterback Alex Smith would become the second NFL quarterback since the merger in 1970 to open his first season with a team by winning his first seven starts.
| Player | Team | Year | Wins | Season |
| Dieter Brock | LA Rams | 1985 | 7 | 11-5, lost NFC championship |
| Brett Favre | Minnesota | 2009 | 6 | 12-4, lost NFC championship |
| John Hadl | LA Rams | 1973 | 6 | 12-2, lost first-round NFC playoff |
| Kyle Orton | Denver | 2009 | 6 | 8-8, no playoffs |
| Alex Smith | Chiefs | 2013 | 6 | TBD |
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